Clinical Trials

Clinical Trials

Clinical Research at the US HAEA Angioedema Center

  • A national registry of individuals with HAE for research in understanding the symptoms, treatments, and underlying genetic causes of HAE in pursuit of a cure.
  • A study of blood samples from individuals with HAE-C1INH deficiency to determine why mutant C1INH proteins inhibit normal C1INH protein activity
  • A study of blood samples to develop and refine laboratory tests that will improve accurate diagnosis of bradykinin-mediated angioedema
  • A study of the safety and efficacy of a subcutaneous treatment to reduce kallikrein activity for the prevention of angioedema attacks in HAE-normal C1INH
If you would like more information or have any questions about research activities, please contact the Angioedema Center by calling at 858-657-5350 or you can e-mail us at


The US HAEA Angioedema Center is screening / enrolling for a study of an investigational medication for the treatment / prevention of hereditary angioedema attacks.

The purpose of this study is to evaluate the safety and tolerability of two dose regimens administered as prophylaxis against hereditary angioedema (HAE) attacks and to evaluate the efficacy of two dose regimens administered as prophylaxis against HAE attacks.

Please contact us for more information if interested:
Marc Riedl, MD, MS
Michelle Boyle, Study Coordinator
Phone: (858) 657-5366